HISTOPATHOLOGICAL FINDINGS OF THYROID NEOPLASMS AND THEIR CORRELATION WITH SERUM TSH, T3, T4 LEVEL IN PATIENTS AT TERTIARY CARE HOSPITAL LUMHS JAMSHORO, PAKISTAN

Abstract

The current study was conducted to determine the association between Histopathological types of thyroid neoplasms and the effect of hormonal level of TSH, T3 and T4 in patients having thyroid neoplasms. The 151 patient were observed in Tertiary care hospital LUMHS Jamshoro & Hyderabad Sindh, Pakistan. Blood sample were collected in Red Top Plain Tube for the hormonal analysis of Thyroid Profile on Automatic analyzer, after surgical procedure Histopathological results were observed. The Data was divided into 7 groups the mean age were observed as 33.67 ± 10.727 years The majority of people affected were found to be between the ages of 30 and 40. It was discovered during observation that there were approximately 134 (88.7%) females, which was a higher ratio than the 17 (11.3%) males. The mean of T3 was observed as 1.49 with S.td 0.619 range from 0 to 4. And the mean of T4 was 8.176 with Std 3.512 ranges from 0.77 to 20.44. While mean of TSH obtained 3.291 with Std 8.874 and the range from 0.001 to 100.0 were obtained. After observation the findings indicate a weakly positive relationship between T3 and age. This study, however, was not significant (r=0.66) (p=420). Additionally, the results indicate a modest negative connection between T4 and age. The results of this investigation were not significant (r=.073) (p=371). The study's findings indicate a negative connection between TSH and age, which was not statistically significant (r=-.092) or p=.263). Laboratory diagnosis and Histopathological results did not significantly correlate (p=.155).